Cancer Prevention Research Meeting Calendar Sign up for eTOC's!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cancer Prevention Research
Cancer Prevention Journals Portal Cancer Reviews Online
Annual Meeting Education Book Meeting Abstracts Online
Cancer Prevention Research 2, 919, November 1, 2009. doi: 10.1158/1940-6207.CAPR-09-0207
© 2009 American Association for Cancer Research
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Related Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Shin, D. M.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shin, D. M.
Related Collections
Right arrowKey Article

Perspectives

Oral Cancer Prevention Advances with a Translational Trial of Green Tea

Dong M. Shin

Author's Affiliation: Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia

Requests for reprints: Dong M. Shin, Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University 1365C Clifton Road, Room C3094, Atlanta, GA 30322. Phone: 404-778-5990; Fax: 404-778-5520; E-mail: dmshin{at}emory.edu.

This perspective on Tsao et al. (beginning on p. 931 in this issue of the journal) discusses green tea extract, which was shown for the first time to have dose-dependent effects in a clinical chemopreventive setting (oral premalignant lesions). This translational trial provides important data on angiogenesis and other biomarkers on which to base future clinical research, which should include trials of green tea extract or polyphenols combined with other natural or synthetic compounds to enhance chemopreventive effects.


Key Article

Phase II Randomized, Placebo-Controlled Trial of Green Tea Extract in Patients with High-Risk Oral Premalignant Lesions
Anne S. Tsao, Diane Liu, Jack Martin, Xi-ming Tang, J. Jack Lee, Adel K. El-Naggar, Ignacio Wistuba, Kirk S. Culotta, Li Mao, Ann Gillenwater, Yuko M. Sagesaka, Waun K. Hong, and Vassiliki Papadimitrakopoulou
Cancer Prevention Research 2009 2: 931-941. [Abstract] [Full Text] [PDF]





HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cancer Prevention Research
Cancer Prevention Journals Portal Cancer Reviews Online
Annual Meeting Education Book Meeting Abstracts Online
Copyright © 2009 by the American Association for Cancer Research.