Table 2.

Predictive accuracy of EDNRB, HOXA9, GATA4, NID2, MCAM, KIF1A, DCC, and CALCA with oral squamous cell carcinoma. Discovery screen (n = 36); prevalence screen (n = 92)

PredictorSensitivity (%)Specificity (%)AUCMethylation cutoff value
Discovery screen
 HOXA9681000.8113.11
 NID2711000.7911.48
 GATA457890.720.96
 KIF1A77920.797.14
 EDNRB681000.8317.42
 DCC55920.749.04
 MCAM36580.4513.44
 CALCA46830.6712.85
Prevalence screen
 HOXA985970.9113.11
 NID287950.9211.48
 HOXA9 and NID294970.97a
  • aClassified positive (+) if predicted probability for positive outcome (tumor) ≥ 0.5.