Table 5.

Comparing sensitivity at 95% specificity for phase II and III results

MarkerPhase IIPhase III
All casesCases diagnosed ≤6 mo after drawCases diagnosed >6–12 mo after drawCases diagnosed >12–18 mo after drawCases diagnosed >18 mo after draw
CA1250.730.860.330.120.03
HE40.570.730.230.180.12
Transthyretin0.470.020.050.120.09
CA15.30.460.450.050.270.03
CA72.4a0.400.440.140.200.06
IGFBP20.380.090.000.000.03
Mesothelin0.350.400.000.060.00
Prolactin0.340.130.090.120.03
Apoliprotein0.340.070.050.120.19
Spondin-20.280.110.140.060.12
Transferrin0.230.090.090.000.00
MIF0.150.180.090.000.18
B2M0.050.090.050.000.15
  • aAssay changed between phase II and phase III (see Materials and Methods).