Table 2.

Health outcomes among probands exposed to primary genetic screening strategies relative to current practice patterns

Screening strategyReduction of colorectal cancer incidence in carriers exposed to screening strategy (%)Reduction of endometrial cancer incidence in carriers exposed to screening strategy (%)Absolute life-years saved per carrier exposed to screening strategy (y)
StrategyScreening start-age (y)Risk threshold (%)
 1200.043.939.64.07
 2250.043.639.23.99
 3300.042.838.83.81
 4350.039.538.23.48
 5400.033.237.52.94
 6202.524.217.22.00
 7252.523.617.01.95
 8302.522.616.61.87
 9352.521.215.81.74
10402.519.314.61.56
11205.013.89.21.11
12255.013.59.01.09
13305.013.08.71.07
14355.012.28.10.99
15405.011.07.30.88
162010.07.04.70.56
172510.06.94.60.54
183010.06.64.50.52
193510.06.14.10.47
204010.05.33.60.41