Table 1.

Differentially expressed genes in the oral mucosa of smokers versus never smokers with corresponding fold changes and P values

Gene nameAffymetrix IDFoldPGene title
S100A7205916_at4.43.1E−02S100 calcium binding protein A7
RPTN1553454_at4.31.7E−02Repetin
CYP1B1202437_s_at4.21.4E−11Cytochrome P450, family 1, subfamily B, polypeptide 1
CYP1B1202436_s_at3.26.9E−10Cytochrome P450, family 1, subfamily B, polypeptide 1
LOR207720_at3.29.4E−03Loricrin
CEACAM7206198_s_at3.03.1E−02Carcinoembryonic antigen-related cell adhesion molecule 7
CYP1A1205749_at2.51.1E−07Cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1202435_s_at2.52.7E−08Cytochrome P450, family 1, subfamily B, polypeptide 1
HTR3A216615_s_at2.27.7E−035-Hydroxytryptamine (serotonin) receptor 3A
GPX2202831_at2.13.1E−04Glutathione peroxidase 2 (gastrointestinal)
FCGBP203240_at2.02.9E−05Fc fragment of IgG binding protein
227452_at2.07.8E−10Full-length cDNA clone CS0DD005YM12 of neuroblastoma Cot 50-normalized of Homo sapiens (human)
CCL26223710_at1.92.8E−02Chemokine (C-C motif) ligand 26
PNLIPRP31558846_at1.96.2E−03Pancreatic lipase-related protein 3
ALOX12B207381_at1.91.2E−02Arachidonate 12-lipoxygenase, 12R type
LOC388610227862_at1.92.9E−02Hypothetical LOC388610
CD207220428_at1.81.3E−05CD207 molecule, langerin
CHRNA3210221_at1.72.0E−04Cholinergic receptor, nicotinic, α3
CYTL1219837_s_at1.71.6E−07Cytokine-like 1
NQO1201468_s_at1.76.7E−04NAD(P)H dehydrogenase, quinone 1
NQO1210519_s_at1.62.1E−03NAD(P)H dehydrogenase, quinone 1
NQO1201467_s_at1.54.9E−03NAD(P)H dehydrogenase, quinone 1
CLEC7A1555756_a_at1.61.6E−02C-type lectin domain family 7, member A
CLEC7A221698_s_at1.69.4E−04C-type lectin domain family 7, member A
LOC344887241418_at1.66.2E−03Similar to hCG2041270
PTGES210367_s_at1.64.9E−02Prostaglandin E synthase
KRT10207023_x_at1.63.5E−02Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
C10orf99227736_at1.69.4E−03Chromosome 10 open reading frame 99
C10orf99227735_s_at1.61.2E−02Chromosome 10 open reading frame 99
ALDH3A1205623_at1.62.9E−05Aldehyde dehydrogenase 3 family, memberA1
ALOX15B206714_at1.63.5E−02Arachidonate 15-lipoxygenase, type B
UGT1A6 /// UGT1A8 /// UGT1A9221305_s_at1.51.1E−02UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A8 /// UDP glucuronosyltransferase 1 family, polypeptide A9
MUC1213693_s_at1.54.7E−02Mucin 1, cell surface associated
AKR1C1 /// AKR1C21555854_at1.51.9E−02Aldo-keto reductase family 1, member C1 /// aldo-keto reductase family 1, member C2
AHRR /// PDCD6229354_at1.53.8E−08Aryl-hydrocarbon receptor repressor /// programmed cell death 6
LYPD5236039_at1.54.7E−02LY6/PLAUR domain containing 5
UGT1A1 /// UGT1A3 to UGT1A10215125_s_at1.52.3E−03UDP glucuronosyltransferase 1 family, polypeptide /// UDP glucuronosyltransferase 1 family, polypeptide A3 to A10
CCL51405_i_at1.51.7E−02Chemokine (C-C motif) ligand 5
UGT1A1 /// UGT1A4 /// UGT1A6 /// UGT1A8 to UGT1A10207126_x_at1.53.1E−04UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glucuronosyltransferase 1 family, polypeptide A4 /// UDP glucuronosyltransferase 1 family, polypeptide A6 /// UDP glucuronosyltransferase 1 family, polypeptide A8 to A10
CD1a210325_at1.59.6E−03CD1a molecule
LYVE1220037_s_at−1.51.0E−02Lymphatic vessel endothelial hyaluronan receptor 1
YOD1215150_at−1.53.0E−02YOD1 OTU deubiquinating enzyme 1 homologue (S. cerevisiae)
CCL18209924_at−1.53.2E−02Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
ANKRD37227337_at−1.53.7E−02Ankyrin repeat domain 37
SOX9202936_s_at−1.52.4E−03SRY (sex determining region Y)-box 9
SOX9202935_s_at−1.51.1E−02SRY (sex determining region Y)-box 9
LEPR211355_x_at−1.54.4E−03Leptin receptor
LEPR211354_s_at−1.64.3E−03Leptin receptor
LEPR211356_x_at−1.62.4E−03Leptin receptor
IGF2BP3203819_s_at−1.75.4E−04Insulin-like growth factor 2 mRNA binding protein 3
IGF2BP3203820_s_at−1.61.4E−02Insulin-like growth factor 2 mRNA binding protein 3
CCL1832128_at−1.63.4E−02Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
HIG21554452_a_at−1.93.8E−02Hypoxia-inducible protein 2
PEG3209242_at−2.11.1E−02Paternally expressed 3

NOTE: Detailed annotations are provided at http://physiology.med.cornell.edu/go/smoke.