Table 4.

Frequency of anticipated adverse events

Adverse eventFrequency, n (%)
Single eventsPer subject
Diarrhea
    Grade 14 (8%)2 (4%)
    Grade 22 (4%)1 (2%)
Flatulence
    Grade 110 (20%)10 (20%)
    Grade 22 (4%)2 (4%)
GI symptom
    Grade 122 (44%)18 (36%)
    Grade 23 (6%)3 (6%)
Irregular menses
    Grade 115 (30%)13 (26%)
Rash
    Grade 11 (2%)1 (2%)
    Grade 210 (20%)6 (12%)
Hot flashes
    Grade 12 (4%)2 (4%)
    Grade 21 (2%)1 (2%)