Table 2

Characteristics of study participants by UGT1A1 genotype

UGT1A1 *1/*1, n = 29 (41%)UGT1A1 *1/*28, n = 36 (51%)UGT1A1 *28/*28, n = 5 (7%)P*
Age (y)32 ± 7.1633 ± 5.5031 ± 6.020.74
Height (m)1.7 ± 0.111.7 ± 0.091.7 ± 0.140.79
Weight (kg)71.0 ± 15.9668.4 ± 13.8672.74 ± 12.370.93
Body mass index (kg/m2)20.7 ± 3.820.1 ± 3.324.4 ± 2.40.98
Female (%)45% (13)55% (20)60% (3)0.64
Race (%)
 Caucasian48% (14)72% (26)60% (3)0.08
 Asian48% (14)17% (6)40% (2)
 Other0.03% (1)0.11% (4)0
GSTT1/GSTM1 genotype0.96
 (+/+), 46% female12122
 (−/+), 50% female11172
 (−/−), 64% female671
Serum bilirubin§ (μmol/L)
 Total14.02 ± 4.9614.02 ± 4.7925.31 ± 9.750.01
 Direct1.88 ± 0.681.88 ± 0.513.25 ± 1.030.01
 Indirect12.14 ± 4.4512.14 ± 4.4522.06 ± 8.890.02
  • *Tests for a trend across UGT1A1 genotypes (χ2).

  • Mean ± SD.

  • Other includes African-Americans and Pacific Islanders.

  • §When consuming habitual diets.