Table 1

Hereditary forms of PDAC

SyndromeDefective gene(s) or chromosomeGenetic testing
Family XChromosome 4q32-34; palladin is candidate geneNo
Hereditary pancreatitisPRSS1Yes
FAMMMp16INK4a/CDKN2AYes
PJLKB1Yes
Hereditary breast/ovarian cancerBRCA1 or BRCA2Yes
Fancomi anemiaBRCA or FANCC, FANCGYes