Table 1

Characteristics of the first and second colonoscopies in patients with prior significant sporadic neoplasia or LS

First colonoscopySecond, randomized colonoscopy
LSSporadic neoplasiaLSSporadic neoplasia
Intensive examChromoendoscopyChromoendoscopy relative to intensive inspectionIntensive examChromoendoscopyChromoendoscopy relative to intensive inspection
Subjects545026282327
Procedure time (min)18.2 ± 8.020.825.3 ± 5.829.8 ± 9.5+4.5 (+18%)27.3 ± 6.236.9 ± 14.5+9.6 (+35%)
Total polyps1761815+88%1035+250%
Subjects with polyps13 (24%)25 (50%)5 (19%)10 (36%)+89%8 (35%)17 (63%)+80%
Polyps per subject0.3 ± 0.61.0-1.40.3 ± 0.70.5 ± 0.8+67%0.4 ± 0.71.3 ± 1.4+225%
Polyps “missed” on first exam2345
Polyp missed rate58%42%
Subjects with biopsies15 (28%)27 (54%)9 (35%)15 (54%)+54%12 (52%)19 (70%)+35%
Total adenomas104075−29%519+280%
Subjects with adenomas8 (15%)17 (34%)5 (19%)3 (11%)−42%4 (17%)12 (44%)+159%
Adenomas per subject0.2 ± 0.50.7-0.90.3 ± 0.60.2 ± 0.5−33%0.2 ± 0.50.7 ± 1.0+250%
Adenomas missed on first exam1224
Adenoma missed rate55%38%