Table 1

Distribution of case patients and control subjects by selected variables

VariableFormer smokersCurrent smokers
Case patients (n = 375)Control subjects (n = 371)PCase patients (n = 350)Control subjects (n = 244)P
Sex
 Male222 (59.20)232 (62.53)181 (51.71)125 (51.23)
 Female153 (40.80)139 (37.47)0.351169 (48.29)119 (48.77)0.907
Age
 Mean (SD)64.8 (8.9)62.5 (9.7)0.00158.0 (10.1)58.5 (9.4)0.495
Pack-year
 Mean (SD)48.7 (31.5)42.3 (31.1)0.00557.6 (29.0)47.5 (29.0)<0.001
DNA repair (DRC), %
 Mean (SD)8.2 (2.6)9.0 (3.5)<0.0018.3 (2.9)9.2 (3.6)0.002
 Median (range)8.0 (0.35–17.63)8.6 (2.39–23.95)8.1 (2.78–25.55)8.7 (2.09–27.21)
Bleomycin sensitivity, breaks/cell
 Mean (SD)0.8 (0.4)0.7 (0.4)<0.0010.7 (0.4)0.6 (0.3)<0.001
 Median (range)0.7 (0.10–3.24)0.6 (0.08–2.36)0.7 (0.04–2.74)0.5 (0.02–2.34)

Abbreviation: DRC, DNA repair capacity.