Table 2

Multivariable logistic models for predicting lung cancer

ParameterLevelsRegression coef.POR (95% CI)
Former smokers
 EmphysemaNo
Yes0.73420.00362.08 (1.27-3.42)
 Dust exposuresNo
Yes0.49330.00291.64 (1.18-2.27)
 Family cancer history0 or 1
 First-degree relatives with cancer≥20.53750.00251.71 (1.21-2.43)
 Age stopped smoking (y)<42
42–530.49590.01481.64 (1.10-2.45)
≥540.9603<0.00012.61 (1.76-3.89)
 Hay feverYes
No0.52740.0111.69 (1.13-2.55)
 DNA repair capacity (% decrease)0.1069<0.00011.11 (1.06-1.17)
 Bleomycin sensitivity (breaks/cell increase)0.62430.00291.87 (1.24-2.82)
Current smokers
 EmphysemaNo
Yes0.90960.00052.48 (1.48-4.16)
 Pack-years<28
28–41.90.28900.31621.34 (0.76-2.35)
42–57.40.30360.27521.36 (0.79-2.34)
≥57.50.51600.04781.68 (1.01-2.79)
 Family cancer history0
 First-degree relatives with (smoking-related cancer)>10.70360.00222.02 (1.29-3.17)
 Hay feverYes
No0.41020.08421.51 (0.95-2.40)
 DustsNo
Yes0.32580.08821.39 (0.95-2.02)
 AsbestosNo
Yes0.55280.05161.74 (1.00-3.03)
 DNA repair capacity (% decrease)0.07090.01311.07 (1.02-1.14)
 Bleomycin sensitivity (breaks/cell increase)1.4665<0.00014.33 (2.45-7.66)