Table 3.

Effect of dietary protein amount, protein type, and resistant starch supplementation on distal colon epithelial cell kineticsa

Treatment groupsPb
Low caseinHigh caseinHigh casein + RSLow meatHigh meatHigh meat + RSProtein amountProtein typeRS
Crypt height (cells)22.3 ± 0.521.9 ± 0.623.1 ± 0.422.5 ± 0.622.3 ± 0.423.2 ± 0.40.620.590.03
Proliferation (cells per crypt)3.7 ± 0.23.3 ± 0.23.7 ± 0.33.5 ± 0.23.5 ± 0.14.2 ± 0.40.390.850.04
Apoptosis (cells per crypt)0.3 ± 0.10.2 ± 0.10.2 ± 0.030.3 ± 0.10.3 ± 0.10.1 ± 0.020.370.730.001

Abbreviation: RS, resistant starch.

  • aValues expressed as means ± SE (n = 12).

  • bUnivariate ANOVA was used to determine the main effect of protein amount, protein type, and resistant starch supplementation.