Table 3.

Methyl DNA adduct formation (pmol adduct/nmol G)

GroupsLiverLung (pool)
O6−MG7-MGO6−MG7-MG
Untreated/Control dietn.d.0.29 ± 0.04n.d.0.56
NNK treated/Control diet5.18 ± 1.333.28 ± 1.3911.213.3
NNK treated/ISC-4 diet1.75 ± 1.31a2.54 ± 0.08n.d.n.d.

Abbreviation: n.d., not detected.

  • aP = 0.0031 versus NNK treated/Control diet.