Table 2.

Pyridyloxobutyl (pob) DNA adduct formation (fmol adduct/nmol G/T)

GroupsLiverLung
O2-pob dTO6-pob dGO2-pob dTO6-pob dG
Untreated/Control dietn.d.n.d.n.d.n.d.
NNK treated/Control diet16.2 ± 4.752.29 ± 0.872.98 ±1.240.20 ± 0.35
NNK treated/ISC-4 diet22.0 ± 5.62n.s1.78 ± 0.90n.s.1.95 ± 0.84n.sn.d.

Abbreviations: n.s., not significant; n.d., not detected.

P = 0.35, 0.57, and 0.33.