Table 2.

Frequencies and distributions for selected characteristics and known breast cancer risk factors in the first 521 participants of the Komen Tissue Bank

Menopausal statusa
All women(N = 521)Premenopausal (N = 351)Postmenopausal (N = 159)Pb
n (%)n (%)n (%)
Age, mean (SD)39.9 (15.1)32.5 (10.2)56.2 (11.0)
Age, min–max18.4–83.118.4–55.827.4–83.1
Education level<0.0001
 High school/GED/or less155 (29.75)118 (33.62)34 (21.38)
 Vocational/tech school or associates degree74 (14.20)36 (10.26)36 (22.64)
 College degree172 (33.01)129 (36.75)39 (24.53)
 Graduate/professional degree113 (21.69)65 (18.52)46 (28.93)
Race0.16
 White446 (85.60)301 (85.75)136 (85.53)
 Black30 (5.76)15 (4.27)14 (8.81)
 Asian3 (0.58)2 (0.57)1 (0.63)
 American Indian/Alaskan native5 (0.96)4 (1.14)1 (0.63)
 Other/missing37 (7.10)29 (8.26)7 (4.40)
Ethnicity0.03
 Hispanic56 (10.75)45 (12.82)10 (6.29)
 Non-Hispanic462 (88.68)306 (87.18)147 (92.45)
Age at menarche, y0.47
 ≤11103 (19.77)69 (19.66)32 (20.13)
 12152 (29.17)105 (29.91)42 (26.42)
 13157 (30.13)110 (31.34)44 (27.67)
 ≥14107 (20.54)67 (19.09)39 (24.53)
BMI, kg/m2<0.0001
 <25212 (40.69)165 (47.01)42 (26.42)
 25–29142 (27.26)94 (26.78)45 (28.30)
 ≥30159 (30.52)88 (25.07)68 (42.77)
No. of full-term births<0.0001
 Nulliparous247 (47.41)215 (61.25)27 (16.98)
 160 (11.52)34 (9.69)25 (15.72)
 2118 (22.65)58 (16.52)57 (35.85)
 ≥391 (17.47)42 (11.97)47 (29.56)
Age at first full-term birth among parous women (n = 269), y0.01
 <2040 (14.87)25 (18.66)13 (10.08)
 20–2471 (26.39)29 (21.64)41 (31.78)
 25–2983 (30.86)35 (26.12)47 (36.43)
 ≥3070 (26.02)43 (32.09)25 (19.38)
Breastfeeding among parous women (n = 269)0.22
 Never66 (24.54)27 (20.15)38 (29.46)
 <24 mo157 (58.36)83 (61.94)71 (55.04)
 ≥24 mo46 (17.10)24 (17.91)20 (15.50)
Oral contraceptive use
 Noncurrent user229 (65.24)
 Current user122 (34.76)
Hormone replacement therapy use
 Never74 (46.54)
 Current/recent use21 (13.21)
 Past use/former64 (40.25)
Family history of breast or ovarian cancer in first-degree relatives0.01
 No388 (74.47)272 (77.49)106 (66.67)
 Yesc133 (25.53)79 (22.51)53 (33.33)
Ever had a breast biopsy<0.0001
 Never430 (82.53)313 (89.17)106 (66.67)
 Ever
  Yes, 163 (12.09)27 (7.69)35 (22.01)
  Yes, 2+20 (3.84)5 (1.42)15 (9.43)
Ever had a screening mammogram<0.0001
 No229 (43.95)216 (61.54)10 (6.29)
 Yes290 (55.66)133a (37.89)149 (93.71)
Smoking<0.0001
 Never357 (68.52)263 (74.93)90 (56.60)
 Former116 (22.26)60 (17.09)53 (33.33)
 Current39 (7.49)22 (6.27)14 (8.81)

NOTE: Differences between cell counts in table and total number are due to missing questionnaire data.

cOf these, 91 women (69%) are age 40 and older and 13 (10%) have a history of breast cancer in a first-degree relative under age 40.

  • aWomen were considered premenopausal if they reported having had a period within 12 months from the questionnaire date or reported taking oral contraceptives. Women were considered postmenopausal if they reported having their last period more than 12 months from the questionnaire date, reported having a hysterectomy, or reported both ovaries removed.

  • bχ2 test to determine if risk factor distributions are significantly different between premenopausal and postmenopausal women.