Table 3.

Total genistein and daidzein concentration in plasma and urine

Genistein, ng/mLDaidzein, ng/mL
Treatment groupTime pointNPlasmaUrinePlasmaUrine
BaselinePlacebo170 ± 0 (0)59.3 ± 98.5 (21.1)2.2 ± 6.6 (0)305 ± 420 (61.7)
300 mg1822.6 ± 93.9 (0)212 ± 551 (47.4)0.6 ± 2.5 (0)650 ± 1,610 (281.0)
600 mg180 ± 0 (0)34.9 ± 39.0 (24.9)24.7 ± 79 (0)1,545 ± 5,815 (135.9)
Day 8Placebo151.8 ± 7.0 (0)57.2 ± 116 (23.6)3.9 ± 6.8 (0)236 ± 258 (120.0)
300 mg1923.0 ± 69.6 (0–3.7)1,235 ± 2,128 (115.5)240 ± 982 (0–3.1)796 ± 1,054 (452.8)
600 mg1811.2 ± 14.2 (0–3.7)648 ± 762 (288.0)4.3 ± 6.4 (0–3.1)975 ± 1,121 (486.7)
PresurgeryPlacebo150 ± 0 (0)34.2 ± 33.8 (23.9)1.3 ± 3.3 (0)177 ± 230 (72.4)
300 mg1922.9 ± 82.4 (0–3.7)848 ± 977 (507.2)54.2 ± 219 (0–3.1)981 ± 741 (852.9)
600 mg183.4 ± 5.9 (0–3.7)1,055 ± 1,129 (680.0)96.1 ± 315 (0–3.1)1,693 ± 2,731 (1,026.5)

NOTE: Values are expressed as mean ± SD (median values).