Table 4.

Phosphorylated EGFR in normal-appearing and tumor tissue

Tissue typeGradePlacebo, n (%)300 mg, n (%)600 mg, n (%)
N = 9N = 14N = 8
BenignNegative2 (22)1 (7)2 (25)
Weak4 (44)4 (29)4 (50)
Moderate3 (33)8 (57)2 (25)
Strong0 (0)1 (7)0 (0)
N = 15N = 19N = 18
TumoraNegative0 (0)0 (0)0 (0)
Weak1 (7)5 (26)0 (0)
Moderate0 (0)4 (21)3 (17)
Strong14 (93)10 (53)15 (83)
  • aP value (placebo vs. all genistein) = 0.07; P value (placebo vs. 300 mg) = 0.015.