Table 1.

Characteristics of study groups

CharacteristicHealthy participantsCancer participantsPa
Agen114112<0.0001
Mean (SD)54 (12.5)67 (13.6)
Male gendern (% Male)70/114 (61)66/112 (59)0.70
Hematocritn10281<0.0001
Mean (SD)0.42 (0.04)0.36 (0.05)
Current smokern (% Yes)41/114 (36)57/94 (61)b<0.0001
MTHFR C677Tb
 CCn (%)43 (38)50 (45)0.57
 CTn (%)53 (47)47 (42)
 TTn (%)18 (16)15 (13)
Region of mucosa sampled
 Right-colonn (%)48/102 (47)45/111 (40)0.06
 Left-colonn (%)37/102 (36)32/111 (29)
 Rectaln (%)17/102 (17)34/111 (31)
  • aStatistical significance was calculated using t tests (mean age, hematocrit, and current smoker) and χ2 tests for all other variables. Significant P values are indicated in bold.

  • bThe MTHFR C677T genotype distribution was confirmed to be in Hardy–Weinberg equilibrium in both healthy and cancer participants.