Table 3.

Univariate analysis: correlationsa (P value) with urinary biomarkers (N = 344–358)

TNE nmol/mg creatinineTotal NNAL pmol/mg creatinineTotal NNN pmol/mg creatinine
Age when first used snuff−0.18 (0.001)−0.18 (0.001)−0.09 (0.088)
Number of years using snuff daily0.50 (<0.001)0.52 (<0.001)0.42 (<0.001)
Dependence score0.22 (<0.001)0.16 (0.003)0.13 (0.012)
Median dip weight (g)−0.001 (0.980)0.06 (0.297)0.02 (0.686)
Tins per week0.36 (<0.001)0.36 (<0.001)0.31 (<0.001)
Mean dips per day0.45 (<0.001)0.41 (<0.001)0.34 (<0.001)
Mean duration per dip (minutes)0.40 (<0.001)0.36 (<0.001)0.32 (<0.001)
Mean daily dip duration (hours)0.67 (<0.001)0.61 (<0.001)0.53 (<0.001)
Free nicotine mg/g wet weight−0.10 (0.069)−0.002 (0.956)−0.03 (0.522)
NNK μg/g wet weight0.23 (<0.001)
NNK/Free nicotine0.22 (<0.001)
NNN μg/g wet weight0.25 (<0.001)
NNN/free nicotine0.28 (<0.001)
  • aThe nonparametric Spearman correlation coefficient.