Table 2.

Change from week 0 to week 24 for HCC biomarkers, SAMe metabolites, and markers of oxidative stress

ControlSAMeDifference between arms
nWk 0Wk 24Wk 24−Wk 0SDDnWk 0Wk 24Wk 24−Wk 0SDDP
AFP4035.8141.665.8629.214334.6232.69−1.9320.307.780.160
DCP260.981.620.651.49270.961.220.260.980.390.266
AFP-L3267.878.200.343.49277.577.710.141.150.190.789
SAMe41121.47112.38−9.0954.6243102.43516.67414.24744.37−423.33<0.001a
SAH4136.3632.90−3.4613.104332.3648.6816.3328.21−19.78<0.001a
SAM/SAH413.453.540.091.71433.318.625.319.06−5.22<0.001a
Methionine4141.2138.31−2.8923.674339.7140.130.4218.79−3.320.478
tHcy419.749.07−0.682.48438.959.220.272.39−0.940.080
tGSH411.972.260.291.23432.262.710.461.43−0.170.563
MDA413.383.380.001.16432.762.75−0.010.850.010.983
4-HNE411.031.00−0.030.45431.040.85−0.190.720.150.248
  • aMann–Whitney test.