Table 3.

Time sequential analysis of log PSA slopes and treatment effect (d)

Slope of log PSA (n)Placebo (n)Sulphoraphane (n)d in log(ng/mL)/moP
M0–M3 (n = 76)0.061 (40)0.046 (36)−0.0150.09
M3–M6 (n = 75)0.049 (39)0.023 (36)−0.0270.011
M3–M8 (n = 72)0.049 (37)0.023 (35)−0.0260.012
M6–M8 (n = 72)0.057 (37)0.032 (35)−0.0250.15

NOTE: Results for each group are medians of the log PSA slope adjusted to the preintervention slope.