Table 4.

Validation performance of the lung cancer risk models applied to the ever smokers in the EPIC-Germany cohort (N = 20,700)

Discrimination (C-index, 95% CI)Calibrationa(E/O, 95% CI)
Bach model0.81 (0.76–0.86)0.88 (0.72–1.08)
Spitz model0.78 (0.73–0.83)3.75 (3.06–4.60)
LLP model0.79 (0.73–0.83)1.12 (0.92–1.37)
PLCOM20120.81 (0.76–0.86)1.03 (0.87–1.23)
  • aThe expected and observed numbers of lung cancer are 81/92 (Bach), 345/92 (Spitz), 103/92 (LLP), and 130/126 (6-year risk, PLCOM2012).