Table 3.

NSABP DMP-1: Comparison of characteristics related to the counseling session of those who decided to take a SERM and those who decided not to take a SERM to reduce the risk of developing breast cancera

Decision about a SERM (n = 726)
To take (n = 324)Not to take (n =402)
CharacteristicsCategoriesNo. (%)No. (%)ORb(95% CI)Pc
Recommendation from HCPdNo recommendation28 (8.6)171 (42.5)<0.001
Not to take a SERM1 (0.3)45 (11.2)
To take a SERM292 (90.1)180 (44.8)12.08 (7.86–18.57)
Unknown3 (0.9)6 (1.5)
The type of HCP you spoke with theRegular doctor/Regular nurse141 (43.5)154 (38.3)0.01
most at today's appointmentAnother doctor/another nurse158 (48.8)192 (47.8)0.90 (0.66–1.23)
Other22 (6.8)53 (13.2)0.45 (0.26–0.78)
Unknown3 (0.9)3 (0.7)
Talked at today's appointment about:Mammogram and/or breast MRI and/or biopsy results236 (72.8)240 (59.7)1.81 (1.32–2.48)<0.001
Breast cancer prevention289 (89.2)337 (83.8)1.59 (1.03–2.47)0.04
BC family history and/or my BC risk and/or genetic testing300 (92.6)378 (94.0)0.79 (0.44–1.43)0.44
What did the HCP use most whenDid not talk about risk/benefits3 (0.9)9 (2.2)0.24
discussing risk and benefits?Mostly used words124 (38.3)166 (41.3)2.24 (0.59–8.45)
Mostly used numbers167 (51.5)193 (48.0)2.60 (0.69–9.75)
Unknown30 (9.3)34 (8.5)
Did you discuss risks of SERMs atNo or yes, less than two risks28 (8.6)51 (12.7)0.08
today's appointment?Yes, two or more risks296 (91.4)351 (87.3)1.54 (0.94–2.50)
Did you discuss benefits of SERMsNo or yes, less than two benefits76 (23.5)114 (28.4)0.13
at today's appointment?Yes, two or more benefits248 (76.5)288 (71.6)1.29 (0.92–1.81)
  • Abbreviation: BC, breast cancer.

  • aHeadings in bold typeface indicate items considered for multivariate modeling.

  • bOR, the relative odds for SERM uptake, “—” identifies the baseline level of the covariate.

  • cP value is based on the likelihood ratio test, unknowns were excluded for calculation of P values.

  • dFor modeling purposes, the “no recommendation” category was combined with the “recommended not to take” category.