Table 3.

Pathway categorization of significantly (q ≤ 0.1) differentially expressed genes in lung tumor tissues from flaxseed-fed mice compared with control-fed mice

Pathway nameTotal genes in the pathwayIdentified genes in the pathway% Significant genes
ERBB signaling46613.04
MAPK signaling2983010.07
IRS-mediated signaling302309.93
Development biology1,066918.54
FGFR signaling pathway9488.51
VEGF signaling347298.36
PI3K–AKT signaling135118.15
EGFR signaling pathway373308.04
Mitochondrial biogenesis5647.14
Metabolism2,1571426.58
Cytokine signaling in immune system835526.23
Wnt signaling296165.41
Apoptosis17495.17
JNK signaling2214.55
Cellular response to hypoxia6634.55
Cellular response to stress423122.84
Transcription regulation by TP5336471.92
Cell cycle49981.60