Table 1.

Statistical analysis of endpoints generated using OCT in 34 week old mice. Number of animals in different groups is listed in Figure 1B

Table 1A. Summary for total number of adenomas, % of mice with ≥1 adenoma, and total tumor burden deriving from imaging

Total # of adenomasTotal tumor burden
GroupMean ± SDRange% (>0)Mean ± SDRange
Vil-Cre negative K-rasG12D
 AOM-induced no sulindac0.20 ± 0.41a0–120.001.39 ± 2.880–7.15
 Control no sulindac0 ± 000.00 ± 00
 AOM-induced sulindac0 ± 000.00 ± 00
 Control sulindac0 ± 000.00 ± 00
K-ras wt
 AOM-induced no sulindac0.83 ± 1.270–441.6710.89 ± 18.760–62.74
 Control no sulindac0 ± 000.00 ± 00
 AOM-induced sulindac0 ± 000.00 ± 00
 Control sulindac0 ± 000.00 ± 00
K-rasG12D
 AOM-induced no sulindac6.91 ± 4.931–17100.050.43 ± 27.705.34–94.34
 Control no sulindac0 ± 000.00 ± 00
 AOM-induced sulindac1.85 ± 2.540–961.548.57 ± 14.370–51.87
 Control sulindac0.11 ± 0.330–111.111.34 ± 4.010–12.04
  • aMean ± SD.