Table 2.

Plasma cytokine levels on days 1 (pre–BSE-SFN administration) and 28 (post–BSE-SFN administration) with percent change (data pooled from all dosage groups)

Median cytokine concentration (pg/mL)Percent change in cytokine concentration*
Day 1Day 28
EGF2619.5−25.0
Exotaxin22.518.5−17.8
bFGF2923−20.6
G-CSF504.3462−8.4
GM-CSF000.0
HGF352324−8.0
IFNα8165−19.8
IFNγ46.537.5−19.4
IL183428.5−16.2
IL-1RA162139.5−13.9
IL211.511−4.3
IL2R471.5341.5−47.6
IL4000.0
IL5137−46.2
IL660−100.0
IL7000.0
IL8140−100.0
IL10000.0
IL12223218−2.2
IL1322.520−11.1
IL15086
IL17000.0
IP-102221−4.5*
MCP-1231.5211.5−8.6*
MIG11384.5−25.2*
MIP-1α79.565−18.2
MIP-1β7562−17.3*
RANTES3,7663,266−13.3
TNFα106.5−35.0
VEGF000.0
  • NOTE: Cytokine levels were measured using the Cytokine Human 30-Plex Panel for Luminex Platform.

  • *, Values that are statistically significant by the Wilcoxon signed rank test.