Table 4.

Odds ratios for the association between cumulative lifetime alcohol consumption and overall, low-grade and high-grade prostate cancer

Age-adjustedMultivariablea
NOR (95% CI)PtrendOR (95% CI)Ptrend
Overall prostate cancer
 Cumulative lifetime alcohol consumption0.0950.32
  Tertile 1 (<3,094 drinks)97/226Ref.Ref.
  Tertile 2 (3,094–10,659 drinks)115/2091.72 (1.17–2.53)1.51 (0.97–2.35)
  Tertile 3 (≥10,660 drinks)113/2151.50 (1.03–2.19)1.36 (0.64–2.19)
Low-grade prostate cancer
 Cumulative lifetime alcohol consumption0.860.97
  Tertile 1 (<3,094 drinks)79/207Ref.Ref.
  Tertile 2 (3,094–10,659 drinks)89/1831.57 (1.05–2.36)1.41 (0.90–2.22)
  Tertile 3 (≥10,660 drinks)70/1721.12 (0.74–1.70)1.06 (0.64–1.74)
High-grade prostate cancer
 Cumulative lifetime alcohol consumption<0.0010.003
  Tertile 1 (<3,094 drinks)19/147Ref.Ref.
  Tertile 2 (3,094–10,659 drinks)26/1202.11 (1.09–4.09)1.81 (0.84–3.90)
  Tertile 3 (≥10,660 drinks)43/1453.07 (1.67–5.64)3.20 (1.47–6.98)
  • aAdjusted for age, race, DRE, prostate volume, PSA, year of consent, smoking, BMI, and previous prostate biopsy.

  • N represents the number of men diagnosed with overall, low-grade or high-grade prostate cancer, respectively, over the total number of men undergoing prostate biopsy.