Table 3.

Odds ratios for the association between alcohol consumption across different ages and low-grade and high-grade prostate cancer

Age-adjustedMultivariablea
NOR (95% CI)PtrendOR (95% CI)Ptrend
Low-grade prostate cancer (GG 1–2)
 Alcohol consumption, age 15–190.730.81
  0 drinks/week77/235Ref.Ref.
  1–6 drinks/week58/2000.88 (0.62–1.25)0.84 (0.57–1.26)
  ≥7 drinks/week11/360.92 (0.47–1.78)0.94 (0.44–1.99)
 Alcohol consumption, age 20–290.100.051
  0 drinks/week26/94Ref.Ref.
  1–6 drinks/week94/2631.50 (0.96–2.35)1.28 (0.77–2.14)
  ≥7 drinks/week26/1140.89 (0.53–1.52)0.72 (0.38–1.38)
 Alcohol consumption, age 30–390.880.56
  0 drinks/week28/117Ref.Ref.
  1–6 drinks/week83/2371.87 (1.22–2.86)1.64 (1.00–2.68)
  ≥7 drinks/week35/1171.33 (0.81–2.19)1.17 (0.62–2.19)
 Alcohol consumption, age 40–490.420.86
  0 drinks/week41/158Ref.Ref.
  1–6 drinks/week70/2121.66 (1.12–2.45)1.65 (1.03–2.62)
  ≥7 drinks/week35/991.42 (0.88–2.31)1.37 (0.72–2.61)
 Alcohol consumption, current0.260.51
  0 drinks/week68/240Ref.Ref.
  1–6 drinks/week60/1841.39 (0.97–1.99)1.25 (0.82–1.92)
  ≥7 drinks/week18/471.46 (0.81–2.61)1.33 (0.68–2.59)
High-grade prostate cancer (GG 3–5)
 Alcohol consumption, age 15–190.0110.020
  0 drinks/week82/240Ref.Ref.
  1–6 drinks/week79/2211.35 (0.81–2.26)1.30 (0.70–2.42)
  ≥7 drinks/week18/432.76 (1.27–6.03)3.21 (1.22–8.41)
 Alcohol consumption, age 20–290.0250.034
  0 drinks/week26/94Ref.Ref.
  1–6 drinks/week102/2711.76 (0.85–3.63)1.81 (0.75–4.42)
  ≥7 drinks/week51/1392.57 (1.20–5.54)3.14 (1.14–8.65)
 Alcohol consumption, age 30–390.0040.019
  0 drinks/week29/118Ref.Ref.
  1–6 drinks/week99/2531.88 (0.95–3.72)1.66 (0.73–3.78)
  ≥7 drinks/week51/1332.98 (1.46–6.09)3.09 (1.20–8.00)
 Alcohol consumption, age 40–490.0010.007
  0 drinks/week42/159Ref.Ref.
  1–6 drinks/week90/2321.55 (0.84–2.83)1.67 (0.79–3.53)
  ≥7 drinks/week45/1092.90 (1.52–5.54)3.64 (1.45–9.15)
 Alcohol consumption, current0.0620.41
  0 drinks/week82/254Ref.Ref.
  1–6 drinks/week76/2001.29 (0.76–2.18)0.73 (0.37–1.40)
  ≥7 drinks/week21/502.07 (0.98–4.38)1.27 (0.51–3.19)
  • aAdjusted for age, race, DRE, prostate volume, PSA, year of consent, smoking, BMI, previous biopsy, and current alcohol consumption (model for current alcohol consumption is adjusted for past alcohol consumption).

  • N represents the number of men diagnosed with low-grade or high-grade prostate cancer, respectively, over the total number of men undergoing prostate biopsy.