Table 3.

Description of lesions and p53 signatures in the fallopian tube after additional sampling (N = 105)

Case IDLesionYear of RRSOAgeBRCA statusSitePositionLocationLaminin γ 1p53Ki-67Fimbria blocks no.Tube blocks no.Pathology reportSecond reviewer agreement
STICs in the right and left fimbria
1STIC201176BRCA2MSKCCTopRight fimbriaPositiveDiffuse staining<10%20STIC; p53 diffuse & Ki-67 ≥10%Yes
STIC & CancerBottomRight fimbriaPositiveDiffuse staining<10%
2STIC201149BRCA1MSKCCTopRight fimbriaPositiveAbsence/nonabnormal≥10%20No lesionNo
3STIC201144BRCA1YALETopRight fimbriaPositiveDiffuse staining≥10%20STIC; p53 diffuse & Ki-67 ≤10%No
STICBottomRight fimbriaPositiveDiffuse staining≥10%
STICs in the nonfimbrial sections of the right and left tube and p53 signatures/STILs in the right and left tube
1STIC201247BRCA2JHUTopLeft distalPositiveDiffuse<10%17No lesionNo
STIC + p53 signatureBottomLeft distalPositiveDiffuse<10%
p53 signatureTopRight proximalNegativeDiffuse<10%
p53 signatureTopRight proximalNegativeDiffuse<10%
2STIL201050BRCA2JHUBottomLeft distalNegativeDiffuse<10%24No lesionNo
p53 signatureBottomLeft fimbriaNegativeDiffuse<10%
3STIL201157BRCA2JHUBottomLeft distalPositiveDiffuse<10%24No lesionNo
p53 signatureBottomRight fimbriaNegativeDiffuse<10%
4p53 signature201247NegativeJHUTopRight distalNegativeDiffuse<10%06No lesionNo
p53 signatureBottomLeft proximalNegativeDiffuse<10%
5p53 signature201249BRCA1JHUTopRight fimbriaNegativeDiffuse<10%24No lesionNo
p53 signatureBottomRight distalNegativeDiffuse<10%
6p53 signature201240BRCA2JHUBottomRight distalNegativeDiffuse<10%28No lesionNo
7p53 signature201259BRCA2JHUBottomRight fimbriaNegativeDiffuse<10%22No lesionNo
8p53 signature201343BRCA1JHUBottomLeft proximalNegativeDiffuse<10%16No lesionNo
9p53 signature201041BRCA2JHUTopRight fimbriaNegativeDiffuse<10%26No lesionNo
10p53 signature201068NegativeJHUTopLeft fimbriaNegativeDiffuse<10%63No lesionNo