Table 2.

Characteristics of women with and without STICs and/or invasive carcinoma in the fallopian tubes (N = 400)

No STIC/STIL and/or invasive carcinoma (n = 377)STIC/STIL and/or invasive carcinoma (n = 23)
Characteristicsn (%)n (%)Pa
Mean age (SD) at RRSO, years48.1 (8.4)51.9 (9.7)0.04
Raceb0.12
 White345 (91.5)19 (83.3)
 Black15 (4.0)0 (0.0)
 Other16 (4.2)3 (12.5)
 Missing1 (0.3)1 (4.2)
BRCA Status0.62
BRCA 1/2 Positive343 (91.0)23 (100.0)
 VUS/Negative19 (5.0)0 (0.0)
 Missing15 (4.0)0 (0.0)
Personal history of breast cancer0.67
 No211 (56.1)14 (62.5)
 Yes166 (43.9)9 (37.5)
Family history of breast and/or ovarian cancerc1.00
 No72 (19.0)4 (16.7)
 Yes302 (80.2)19 (83.3)
 Missing3 (0.8)0 (0.0)
Parity1.00
 Nulliparous41 (10.8)2 (8.3)
 Parous334 (88.6)21 (91.7)
 Missing2 (0.5)0 (0.0)
Breast feedingd1.00
 No 34 (13.8)2 (10.5)
 Yes165 (66.8)11 (57.9)
 Missing48 (19.4)6 (31.6)
Mean duration of breastfeeding, months (SD)d14.5 (13.2)7.4 (6.02)0.07
Oral contraceptive use0.62
 Never82 (21.7)4 (16.7)
 Ever267 (70.9)19 (83.3)
 Missing28 (7.4)0 (0.0)
Mean duration of oral contraceptive use months (SD)9.6 (6.7)8.5 (2.4)0.58
Hormone therapy use1.00
 Never295 (78.3)17 (75.0)
 Ever51 (13.5)3 (12.5)
 Missing31 (8.2)3 (12.5)
Tubal ligation0.55
 Never313 (83.1)18 (79.2)
 Ever54 (14.3)4 (16.7)
 Missing10 (2.6)1 (4.2)
Hysterectomye0.38
 Never350(92.9)22 (95.8)
 Ever24 (6.3)0(0.0)
 Missing3 (0.8)1 (4.2)
Endometriosis0.33
 Never338 (89.7)18 (79.2)
 Ever19 (5.0)3 (12.5)
 Missing20 (5.3)2 (8.3)
  • NOTE: All values were age standardized.

  • Abbreviations: BRCA, breast cancer susceptibility gene; VUS, variants of uncertain significance.

  • aFisher exact was used for groups with < 10 in one category.

  • bOther includes Hispanic, Asian/Pacific Islander, and those who are multiracial.

  • cThose who reported a first- and/or second-degree family history of breast and/or ovarian cancer.

  • dBreast feeding limited to parous women at JHU and Toronto.

  • eCollected on closest date prior to RRSO.