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Cancer Prevention Research
Cancer Prevention Research
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Research Article

Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma

Feifei Liu, Xueyin Zu, Xiaomeng Xie, Yuanyuan Zhang, Kangdong Liu, Hanyong Chen, Ting Wang, Ann M. Bode, Zigang Dong and Dong Joon Kim
Feifei Liu
1China-US (Henan) Hormel Cancer Institute, Henan, China.
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Xueyin Zu
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
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Xiaomeng Xie
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
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Yuanyuan Zhang
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
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Kangdong Liu
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
3The Affiliated Cancer Hospital, Zhengzhou University, Zhengzhou, Henan, China.
4The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention, Zhengzhou, Henan, China.
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Hanyong Chen
5The Hormel Institute, University of Minnesota, Austin, Minnesota.
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Ting Wang
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
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Ann M. Bode
5The Hormel Institute, University of Minnesota, Austin, Minnesota.
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Zigang Dong
5The Hormel Institute, University of Minnesota, Austin, Minnesota.
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  • For correspondence: djkim@hci-cn.org zgdong@hi.umn.edu
Dong Joon Kim
1China-US (Henan) Hormel Cancer Institute, Henan, China.
2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
4The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention, Zhengzhou, Henan, China.
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  • For correspondence: djkim@hci-cn.org zgdong@hi.umn.edu
DOI: 10.1158/1940-6207.CAPR-19-0244 Published December 2019
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Article Information

Volume 12, Issue 12, pp. 849-860

DOI 
https://doi.org/10.1158/1940-6207.CAPR-19-0244
PubMed 
31554627

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received May 11, 2019
  • Revision received August 10, 2019
  • Accepted September 20, 2019
  • Published first September 25, 2019.

Article Versions

  • Previous version (September 25, 2019 - 07:30).
  • Previous version (November 15, 2019 - 06:29).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Feifei Liu1,
  2. Xueyin Zu1,2,
  3. Xiaomeng Xie1,2,
  4. Yuanyuan Zhang1,2,
  5. Kangdong Liu1,2,3,4,
  6. Hanyong Chen5,
  7. Ting Wang1,2,
  8. Ann M. Bode5,
  9. Zigang Dong5,*, and
  10. Dong Joon Kim1,2,4,*
  1. 1China-US (Henan) Hormel Cancer Institute, Henan, China.
  2. 2The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  3. 3The Affiliated Cancer Hospital, Zhengzhou University, Zhengzhou, Henan, China.
  4. 4The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention, Zhengzhou, Henan, China.
  5. 5The Hormel Institute, University of Minnesota, Austin, Minnesota.
  1. ↵*Corresponding Authors:
    Dong Joon Kim, China-US (Henan) Hormel Cancer Institute, No, 127 Dongming Road, Zhengzhou, Henan 450008, China. Phone: 156-1790-7639; Fax: 371-6558-7227; E-mail: djkim{at}hci-cn.org; and Zigang Dong, The Hormel Institute, University of Minnesota, 801 16th Avenue NE, Austin, MN 55912. Phone: 150-7437-9600; Fax: 150-7437-9606; E-mail: zgdong{at}hi.umn.edu
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Cancer Prevention Research: 12 (12)
December 2019
Volume 12, Issue 12
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Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma
Feifei Liu, Xueyin Zu, Xiaomeng Xie, Yuanyuan Zhang, Kangdong Liu, Hanyong Chen, Ting Wang, Ann M. Bode, Zigang Dong and Dong Joon Kim
Cancer Prev Res December 1 2019 (12) (12) 849-860; DOI: 10.1158/1940-6207.CAPR-19-0244

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Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma
Feifei Liu, Xueyin Zu, Xiaomeng Xie, Yuanyuan Zhang, Kangdong Liu, Hanyong Chen, Ting Wang, Ann M. Bode, Zigang Dong and Dong Joon Kim
Cancer Prev Res December 1 2019 (12) (12) 849-860; DOI: 10.1158/1940-6207.CAPR-19-0244
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