Review
An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis
Karam El-Bayoumy, Neil D. Christensen, Jiafen Hu, Raphael Viscidi, Douglas B. Stairs, Vonn Walter, Kun-Ming Chen, Yuan-Wan Sun, Joshua E. Muscat and John P. Richie Jr.
Karam El-Bayoumy
1Department of Biochemistry & Molecular Biology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Neil D. Christensen
2The Jake Gittlen Laboratories for Cancer Research, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
3Department of Pathology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Jiafen Hu
2The Jake Gittlen Laboratories for Cancer Research, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
3Department of Pathology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Raphael Viscidi
4Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Douglas B. Stairs
3Department of Pathology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Vonn Walter
1Department of Biochemistry & Molecular Biology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
5Department of Public Health Sciences, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Kun-Ming Chen
1Department of Biochemistry & Molecular Biology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Yuan-Wan Sun
1Department of Biochemistry & Molecular Biology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Joshua E. Muscat
5Department of Public Health Sciences, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
John P. Richie Jr.
5Department of Public Health Sciences, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
DOI: 10.1158/1940-6207.CAPR-20-0096 Published August 2020

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August 2020
Volume 13, Issue 8
Volume 13, Issue 8
An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis
Karam El-Bayoumy, Neil D. Christensen, Jiafen Hu, Raphael Viscidi, Douglas B. Stairs, Vonn Walter, Kun-Ming Chen, Yuan-Wan Sun, Joshua E. Muscat and John P. Richie Jr.
Cancer Prev Res August 1 2020 (13) (8) 649-660; DOI: 10.1158/1940-6207.CAPR-20-0096
An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis
Karam El-Bayoumy, Neil D. Christensen, Jiafen Hu, Raphael Viscidi, Douglas B. Stairs, Vonn Walter, Kun-Ming Chen, Yuan-Wan Sun, Joshua E. Muscat and John P. Richie Jr.
Cancer Prev Res August 1 2020 (13) (8) 649-660; DOI: 10.1158/1940-6207.CAPR-20-0096
Jump to section
- Article
- Abstract
- Introduction
- Risk Factors
- Interactions of HPV Proteins with Molecular Targets of Carcinogenesis
- Animal Models for HNSCC
- A Novel Mouse Papillomavirus Model for OSCC and OPSCC
- Genetic Mouse Models for OSCC and OPSCC
- Impact of Oxidative Stress on OSCC and OPSCC
- Interactions of Known Risk Factors with the Oral Microbiome
- Challenges to Disease Prevention
- Summary and Future Directions
- Disclosure of Potential Conflicts of Interest
- Acknowledgments
- Footnotes
- References
- Figures & Data
- Info & Metrics
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