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Cancer Prevention Research
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Research Article

Reducing Fatty Acid Oxidation Improves Cancer-free Survival in a Mouse Model of Li-Fraumeni Syndrome

Ping-Yuan Wang, Jin Ma, Jie Li, Matthew F. Starost, Michael J. Wolfgang, Komudi Singh, Mehdi Pirooznia, Ju-Gyeong Kang and Paul M. Hwang
Ping-Yuan Wang
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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Jin Ma
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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Jie Li
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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Matthew F. Starost
2Division of Veterinary Resources, NIH, Bethesda, Maryland.
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Michael J. Wolfgang
3Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Komudi Singh
4Bioinformatics and Computational Biology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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Mehdi Pirooznia
4Bioinformatics and Computational Biology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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  • ORCID record for Mehdi Pirooznia
Ju-Gyeong Kang
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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Paul M. Hwang
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
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  • ORCID record for Paul M. Hwang
  • For correspondence: hwangp@mail.nih.gov
DOI: 10.1158/1940-6207.CAPR-20-0368 Published January 2021
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Article Information

Volume 14, Issue 1, pp. 31-40

DOI 
https://doi.org/10.1158/1940-6207.CAPR-20-0368
PubMed 
32958587

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received July 8, 2020
  • Revision received August 11, 2020
  • Accepted September 15, 2020
  • Published first September 21, 2020.

Article Versions

  • Previous version (September 21, 2020 - 07:31).
  • Previous version (December 21, 2020 - 07:20).
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Copyright & Usage 
©2020 American Association for Cancer Research.

Author Information

  1. Ping-Yuan Wang1,#,
  2. Jin Ma1,#,
  3. Jie Li1,
  4. Matthew F. Starost2,
  5. Michael J. Wolfgang3,
  6. Komudi Singh4,
  7. Mehdi Pirooznia4,
  8. Ju-Gyeong Kang1, and
  9. Paul M. Hwang1,*
  1. 1Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  2. 2Division of Veterinary Resources, NIH, Bethesda, Maryland.
  3. 3Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  4. 4Bioinformatics and Computational Biology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  1. ↵*Corresponding Author:
    Paul M. Hwang, NHLBI, NIH, 10CRC/5-5330, 10 Center Drive, Bethesda, MD 20892. Phone: 301-435-3068; Fax: 301-402-0888; E-mail: hwangp{at}mail.nih.gov
  1. ↵#P.-Y. Wang and J. Ma contributed equally to this article.

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Cancer Prevention Research: 14 (1)
January 2021
Volume 14, Issue 1
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Reducing Fatty Acid Oxidation Improves Cancer-free Survival in a Mouse Model of Li-Fraumeni Syndrome
Ping-Yuan Wang, Jin Ma, Jie Li, Matthew F. Starost, Michael J. Wolfgang, Komudi Singh, Mehdi Pirooznia, Ju-Gyeong Kang and Paul M. Hwang
Cancer Prev Res January 1 2021 (14) (1) 31-40; DOI: 10.1158/1940-6207.CAPR-20-0368

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Reducing Fatty Acid Oxidation Improves Cancer-free Survival in a Mouse Model of Li-Fraumeni Syndrome
Ping-Yuan Wang, Jin Ma, Jie Li, Matthew F. Starost, Michael J. Wolfgang, Komudi Singh, Mehdi Pirooznia, Ju-Gyeong Kang and Paul M. Hwang
Cancer Prev Res January 1 2021 (14) (1) 31-40; DOI: 10.1158/1940-6207.CAPR-20-0368
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