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Cancer Prevention Research
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Review

Diet-Dependent Metabolic Regulation of DNA Double-Strand Break Repair in Cancer: More Choices on the Menu

Anna de Polo and David P. Labbé
Anna de Polo
Division of Urology, Department of Surgery, McGill University and Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
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David P. Labbé
Division of Urology, Department of Surgery, McGill University and Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
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DOI: 10.1158/1940-6207.CAPR-20-0470 Published April 2021
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Article Information

Volume 14, Issue 4, pp. 403-414

DOI 
https://doi.org/10.1158/1940-6207.CAPR-20-0470
PubMed 
33509805

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received September 9, 2020
  • Revision received November 27, 2020
  • Accepted January 21, 2021
  • Published first January 28, 2021.

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  • Previous version (January 28, 2021 - 14:39).
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©2021 American Association for Cancer Research.

Author Information

  1. Anna de Polo and
  2. David P. Labbé*
  1. Division of Urology, Department of Surgery, McGill University and Cancer Research Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
  1. ↵*Corresponding Author:
    David P. Labbé, Research Institute of the McGill University Health Centre, 1001 Boulevard Décarie, E02.6217, Montréal, Québec, H4A 3J1, Canada. Phone: 514-934-1934, ext. 76361; Fax: 514-933-2875; E-mail: david.labbe{at}mcgill.ca
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Cancer Prevention Research: 14 (4)
April 2021
Volume 14, Issue 4
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Diet-Dependent Metabolic Regulation of DNA Double-Strand Break Repair in Cancer: More Choices on the Menu
Anna de Polo and David P. Labbé
Cancer Prev Res April 1 2021 (14) (4) 403-414; DOI: 10.1158/1940-6207.CAPR-20-0470

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Diet-Dependent Metabolic Regulation of DNA Double-Strand Break Repair in Cancer: More Choices on the Menu
Anna de Polo and David P. Labbé
Cancer Prev Res April 1 2021 (14) (4) 403-414; DOI: 10.1158/1940-6207.CAPR-20-0470
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  • Article
    • Abstract
    • Introduction
    • Diet and Genomic Stability
    • Overview of DSB Repair Pathways
    • Role of Chromatin Status in DSB Repair
    • Role of RNA in DSB Repair
    • m6A RNA Methylation and its Role in Genomic Stability
    • Metabolic Regulation of Methylation
    • Concluding Remarks
    • Authors’ Disclosures
    • Acknowledgments
    • Footnotes
    • References
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Cancer Prevention Research
eISSN: 1940-6215
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