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Cancer Prevention Research
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Research Article

Obesity is Associated with Shorter Telomere Length in Prostate Stromal Cells in Men with Aggressive Prostate Cancer

Corinne E. Joshu, Christopher M. Heaphy, John R. Barber, Jiayun Lu, Reza Zarinshenas, Christine Davis, Misop Han, Tamara L. Lotan, Karen S. Sfanos, Angelo M. De Marzo, Alan K. Meeker and Elizabeth A. Platz
Corinne E. Joshu
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
2Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
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  • ORCID record for Corinne E. Joshu
  • For correspondence: cjoshu1@jhu.edu
Christopher M. Heaphy
4Department of Medicine, Boston University, Boston, Massachusetts.
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John R. Barber
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
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Jiayun Lu
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
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Reza Zarinshenas
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Christine Davis
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Misop Han
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Tamara L. Lotan
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Karen S. Sfanos
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Angelo M. De Marzo
2Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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  • ORCID record for Angelo M. De Marzo
Alan K. Meeker
2Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Elizabeth A. Platz
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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DOI: 10.1158/1940-6207.CAPR-20-0250 Published April 2021
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Article Information

Volume 14, Issue 4, pp. 463-470

DOI 
https://doi.org/10.1158/1940-6207.CAPR-20-0250
PubMed 
33355185

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received May 18, 2020
  • Revision received September 17, 2020
  • Accepted December 9, 2020
  • Published first December 22, 2020.

Article Versions

  • Previous version (December 22, 2020 - 05:56).
  • Previous version (January 20, 2021 - 07:10).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2020 American Association for Cancer Research.

Author Information

  1. Corinne E. Joshu1,2,3,*,
  2. Christopher M. Heaphy4,
  3. John R. Barber1,
  4. Jiayun Lu1,
  5. Reza Zarinshenas5,
  6. Christine Davis5,
  7. Misop Han6,
  8. Tamara L. Lotan3,5,6,
  9. Karen S. Sfanos3,5,6,
  10. Angelo M. De Marzo2,3,5,6,
  11. Alan K. Meeker2,3,5,6, and
  12. Elizabeth A. Platz1,3,5,6
  1. 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
  2. 2Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  3. 3Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
  4. 4Department of Medicine, Boston University, Boston, Massachusetts.
  5. 5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  6. 6Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  1. ↵*Corresponding Author:
    Corinne E. Joshu, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Rm. E6148, Baltimore, MD 21205. Phone: 443-287-3821; Fax: 410-614-2632; E-mail: cjoshu1{at}jhu.edu
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Cancer Prevention Research: 14 (4)
April 2021
Volume 14, Issue 4
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Obesity is Associated with Shorter Telomere Length in Prostate Stromal Cells in Men with Aggressive Prostate Cancer
Corinne E. Joshu, Christopher M. Heaphy, John R. Barber, Jiayun Lu, Reza Zarinshenas, Christine Davis, Misop Han, Tamara L. Lotan, Karen S. Sfanos, Angelo M. De Marzo, Alan K. Meeker and Elizabeth A. Platz
Cancer Prev Res April 1 2021 (14) (4) 463-470; DOI: 10.1158/1940-6207.CAPR-20-0250

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Obesity is Associated with Shorter Telomere Length in Prostate Stromal Cells in Men with Aggressive Prostate Cancer
Corinne E. Joshu, Christopher M. Heaphy, John R. Barber, Jiayun Lu, Reza Zarinshenas, Christine Davis, Misop Han, Tamara L. Lotan, Karen S. Sfanos, Angelo M. De Marzo, Alan K. Meeker and Elizabeth A. Platz
Cancer Prev Res April 1 2021 (14) (4) 463-470; DOI: 10.1158/1940-6207.CAPR-20-0250
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