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Cancer Prevention Research
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Table of Contents

From the Editor

  • From the Editor
    In This Issue
    Scott M. Lippman
    Cancer Prev Res April 1 2012 5 (4) 499-499; DOI:10.1158/1940-6207.CAPR-12-0113

Perspectives

  • Perspectives
    Metformin and Hepatic Carcinogenesis
    Michael Pollak and Ana M. Gonzalez-Angulo
    Cancer Prev Res April 1 2012 5 (4) 500-502; DOI:10.1158/1940-6207.CAPR-12-0080

  • Perspectives
    Prevention of Mutagenesis: New Potential Mechanisms of Metformin Action in Neoplastic Cells
    Frédéric Bost, Issam Ben-Sahra and Jean-François Tanti
    Cancer Prev Res April 1 2012 5 (4) 503-506; DOI:10.1158/1940-6207.CAPR-12-0085

  • Perspectives
    Diagnosing Lynch Syndrome: More Light at the End of the Tunnel
    Randall W. Burt
    Cancer Prev Res April 1 2012 5 (4) 507-510; DOI:10.1158/1940-6207.CAPR-12-0087

  • Perspectives
    Simplifying the Energy Balance Message for Breast Cancer Prevention
    Carol J. Fabian
    Cancer Prev Res April 1 2012 5 (4) 511-514; DOI:10.1158/1940-6207.CAPR-12-0088

MiniReviews

  • MiniReviews
    Obesity and the Risk for Premenopausal and Postmenopausal Breast Cancer
    Garnet L. Anderson and Marian L. Neuhouser
    Cancer Prev Res April 1 2012 5 (4) 515-521; DOI:10.1158/1940-6207.CAPR-12-0091

  • MiniReviews
    Genetic Predisposition to Chronic Obstructive Pulmonary Disease and/or Lung Cancer: Important Considerations When Evaluating Risk
    Randa A. El-Zein, Robert P. Young, Raewyn J. Hopkins and Carol J. Etzel
    Cancer Prev Res April 1 2012 5 (4) 522-527; DOI:10.1158/1940-6207.CAPR-12-0042

Commentary

  • Commentary
    The Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center: A Unique Resource for Defining the “Molecular Histology” of the Breast
    Mark E. Sherman, Jonine D. Figueroa, Jill E. Henry, Susan E. Clare, Connie Rufenbarger and Anna Maria Storniolo
    Cancer Prev Res April 1 2012 5 (4) 528-535; DOI:10.1158/1940-6207.CAPR-11-0234

Research Articles

  • Research Article | Free Article
    Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage
    Carolyn Algire, Olga Moiseeva, Xavier Deschênes-Simard, Lilian Amrein, Luca Petruccelli, Elena Birman, Benoit Viollet, Gerardo Ferbeyre and Michael N. Pollak
    Cancer Prev Res April 1 2012 5 (4) 536-543; DOI:10.1158/1940-6207.CAPR-11-0536

  • Research Article
    Metformin Prevents Liver Tumorigenesis by Inhibiting Pathways Driving Hepatic Lipogenesis
    Kavita Bhalla, Bor Jang Hwang, Ruby E. Dewi, William Twaddel, Olga G. Goloubeva, Kwok-Kin Wong, Neeraj K. Saxena, Shyam Biswal and Geoffrey D. Girnun
    Cancer Prev Res April 1 2012 5 (4) 544-552; DOI:10.1158/1940-6207.CAPR-11-0228

  • Research Article
    Metformin-Mediated Bambi Expression in Hepatic Stellate Cells Induces Prosurvival Wnt/β-Catenin Signaling
    Nanthakumar Subramaniam, Mara H. Sherman, Renuka Rao, Caroline Wilson, Sally Coulter, Annette R. Atkins, Ronald M. Evans, Christopher Liddle and Michael Downes
    Cancer Prev Res April 1 2012 5 (4) 553-561; DOI:10.1158/1940-6207.CAPR-12-0053

  • Research Article
    Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions
    Lynn Vitale-Cross, Alfredo A. Molinolo, Daniel Martin, Rania H. Younis, Takashi Maruyama, Vyomesh Patel, Wanjun Chen, Abraham Schneider and J. Silvio Gutkind
    Cancer Prev Res April 1 2012 5 (4) 562-573; DOI:10.1158/1940-6207.CAPR-11-0502

  • Research Article
    Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps
    Matthew B. Yurgelun, Ajay Goel, Jason L. Hornick, Ananda Sen, Danielle Kim Turgeon, Mack T. Ruffin IV, Norman E. Marcon, John A. Baron, Robert S. Bresalier, Sapna Syngal, Dean E. Brenner, C. Richard Boland and Elena M. Stoffel
    Cancer Prev Res April 1 2012 5 (4) 574-582; DOI:10.1158/1940-6207.CAPR-11-0519

  • Research Article
    Body Mass Index and the Risk for Developing Invasive Breast Cancer among High-Risk Women in NSABP P-1 and STAR Breast Cancer Prevention Trials
    Reena S. Cecchini, Joseph P. Costantino, Jane A. Cauley, Walter M. Cronin, D. Lawrence Wickerham, Stephanie R. Land, Joel L. Weissfeld and Norman Wolmark
    Cancer Prev Res April 1 2012 5 (4) 583-592; DOI:10.1158/1940-6207.CAPR-11-0482

  • Research Article
    Carnosol, a Constituent of Zyflamend, Inhibits Aryl Hydrocarbon Receptor–Mediated Activation of CYP1A1 and CYP1B1 Transcription and Mutagenesis
    Arash Mohebati, Joseph B. Guttenplan, Amit Kochhar, Zhong-Lin Zhao, Wieslawa Kosinska, Kotha Subbaramaiah and Andrew J. Dannenberg
    Cancer Prev Res April 1 2012 5 (4) 593-602; DOI:10.1158/1940-6207.CAPR-12-0002

  • Research Article
    Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the Gastrointestinal Microflora
    Jed W. Fahey, Scott L. Wehage, W. David Holtzclaw, Thomas W. Kensler, Patricia A. Egner, Theresa A. Shapiro and Paul Talalay
    Cancer Prev Res April 1 2012 5 (4) 603-611; DOI:10.1158/1940-6207.CAPR-11-0538

  • Research Article
    The Novel Akt Inhibitor API-1 Induces c-FLIP Degradation and Synergizes with TRAIL to Augment Apoptosis Independent of Akt Inhibition
    Bo Li, Hui Ren, Ping Yue, Mingwei Chen, Fadlo R. Khuri and Shi-Yong Sun
    Cancer Prev Res April 1 2012 5 (4) 612-620; DOI:10.1158/1940-6207.CAPR-11-0548

  • Research Article
    A Phase 2 Cancer Chemoprevention Biomarker Trial of Isoflavone G-2535 (Genistein) in Presurgical Bladder Cancer Patients
    Edward Messing, Jason R. Gee, Daniel R. Saltzstein, KyungMann Kim, Anthony diSant'Agnese, Jill Kolesar, Linda Harris, Adrienne Faerber, Thomas Havighurst, Jay M. Young, Mitchell Efros, Robert H. Getzenberg, Marcia A. Wheeler, Joseph Tangrea, Howard Parnes, Margaret House, J. Erik Busby, Raymond Hohl and Howard Bailey
    Cancer Prev Res April 1 2012 5 (4) 621-630; DOI:10.1158/1940-6207.CAPR-11-0455

  • Research Article
    Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo
    Peramaiyan Rajendran, Feng Li, Muthu K. Shanmugam, Radhamani Kannaiyan, Jen Nee Goh, Kwong Fai Wong, Wei Wang, Ester Khin, Vinay Tergaonkar, Alan Prem Kumar, John M. Luk and Gautam Sethi
    Cancer Prev Res April 1 2012 5 (4) 631-643; DOI:10.1158/1940-6207.CAPR-11-0420

  • Research Article
    δ- and γ-Tocopherols, but not α-Tocopherol, Inhibit Colon Carcinogenesis in Azoxymethane-Treated F344 Rats
    Fei Guan, Guangxun Li, Anna B. Liu, Mao-Jung Lee, Zhihong Yang, Yu-Kuo Chen, Yong Lin, Weichung Shih and Chung S. Yang
    Cancer Prev Res April 1 2012 5 (4) 644-654; DOI:10.1158/1940-6207.CAPR-11-0521

  • Research Article
    Increased Plasma Levels of the APC-Interacting Protein MAPRE1, LRG1, and IGFBP2 Preceding a Diagnosis of Colorectal Cancer in Women
    Jon J. Ladd, Tina Busald, Melissa M. Johnson, Qing Zhang, Sharon J. Pitteri, Hong Wang, Dean E. Brenner, Paul D. Lampe, Raju Kucherlapati, Ziding Feng, Ross L. Prentice and Samir M. Hanash
    Cancer Prev Res April 1 2012 5 (4) 655-664; DOI:10.1158/1940-6207.CAPR-11-0412

  • Research Article
    Oncogenic Function and Early Detection Potential of miRNA-10b in Oral Cancer as Identified by microRNA Profiling
    Ya-Ching Lu, Yin-Ju Chen, Hung-Ming Wang, Chi-Ying Tsai, Wen-Ho Chen, Yu-Chen Huang, Kang-Hsing Fan, Chi-Neu Tsai, Shiang-Fu Huang, Chung-Jan Kang, Joseph Tung-Chieh Chang and Ann-Joy Cheng
    Cancer Prev Res April 1 2012 5 (4) 665-674; DOI:10.1158/1940-6207.CAPR-11-0358

  • Research Article
    A New Biomarker That Predicts Colonic Neoplasia Outcome in Patients with Hyperplastic Colonic Polyps
    Catherine Do, Claudine Bertrand, Julien Palasse, Marie-Bernadette Delisle, Arthur Shulkes, Elizabeth Cohen-Jonathan-Moyal, Audrey Ferrand and Catherine Seva
    Cancer Prev Res April 1 2012 5 (4) 675-684; DOI:10.1158/1940-6207.CAPR-11-0408

  • Research Article
    A Hexane Fraction of American Ginseng Suppresses Mouse Colitis and Associated Colon Cancer: Anti-inflammatory and Proapoptotic Mechanisms
    Deepak Poudyal, Phuong Mai Le, Tia Davis, Anne B. Hofseth, Alena Chumanevich, Alexander A. Chumanevich, Michael J. Wargovich, Mitzi Nagarkatti, Prakash S. Nagarkatti, Anthony Windust and Lorne J. Hofseth
    Cancer Prev Res April 1 2012 5 (4) 685-696; DOI:10.1158/1940-6207.CAPR-11-0421

Letters to the Editor

  • Letter to the Editor
    Lung Cancer Risk Prediction to Select Smokers for Screening CT—Letter
    Robert P. Young and Raewyn J. Hopkins
    Cancer Prev Res April 1 2012 5 (4) 697-698; DOI:10.1158/1940-6207.CAPR-11-0531

  • Letter to the Editor
    Lung Cancer Risk Prediction to Select Smokers for Screening CT—Response
    Patrick Maisonneuve, Vincenzo Bagnardi, Massimo Bellomi and Giulia Veronesi
    Cancer Prev Res April 1 2012 5 (4) 699-699; DOI:10.1158/1940-6207.CAPR-12-0044

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Cancer Prevention Research: 5 (4)
April 2012
Volume 5, Issue 4
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Cancer Prevention Research
eISSN: 1940-6215
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