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Cancer Prevention Research
Cancer Prevention Research
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Research Article

Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions

Lynn Vitale-Cross, Alfredo A. Molinolo, Daniel Martin, Rania H. Younis, Takashi Maruyama, Vyomesh Patel, Wanjun Chen, Abraham Schneider and J. Silvio Gutkind
Lynn Vitale-Cross
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Alfredo A. Molinolo
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Daniel Martin
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Rania H. Younis
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Takashi Maruyama
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Vyomesh Patel
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Wanjun Chen
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Abraham Schneider
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J. Silvio Gutkind
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DOI: 10.1158/1940-6207.CAPR-11-0502 Published April 2012
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Article Information

Volume 5, Issue 4, pp. 562-573

DOI 
https://doi.org/10.1158/1940-6207.CAPR-11-0502
PubMed 
22467081

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received November 7, 2011
  • Revision received February 24, 2012
  • Accepted February 28, 2012
  • Published first April 3, 2012.

Article Versions

  • Previous version (March 31, 2012 - 11:15).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2012 American Association for Cancer Research.

Author Information

  1. Lynn Vitale-Cross1,
  2. Alfredo A. Molinolo1,
  3. Daniel Martin1,
  4. Rania H. Younis3,
  5. Takashi Maruyama2,
  6. Vyomesh Patel1,
  7. Wanjun Chen2,
  8. Abraham Schneider3,4, and
  9. J. Silvio Gutkind1
  1. Authors' Affiliations: 1Molecular Carcinogenesis Section, Oral and Pharyngeal Cancer Branch, and 2Oral Mucosal Immunology Section, Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, NIH; and 3Department of Oncology and Diagnostic Sciences, School of Dentistry and 4Greenebaum Cancer Center, Program in Oncology, University of Maryland, Baltimore, Maryland
  1. Corresponding Authors:
    J.S. Gutkind, NIH, 30 Convent Drive, Bethesda, MD 20892. Phone: 301-496-6259; Fax: 301-402-0823; E-mail: sg39v{at}nih.gov; and A. Schneider, E-mail: aschneider{at}umaryland.edu
  • Current address for T. Maruyama: Laboratory of Cell Recognition and Response, Graduate School of Life Sciences, Tohoku University, Aoba 6-3, Aramaki, Aoba-ku, Sendai 980-8578, Japan.

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Cancer Prevention Research: 5 (4)
April 2012
Volume 5, Issue 4
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Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions
Lynn Vitale-Cross, Alfredo A. Molinolo, Daniel Martin, Rania H. Younis, Takashi Maruyama, Vyomesh Patel, Wanjun Chen, Abraham Schneider and J. Silvio Gutkind
Cancer Prev Res April 1 2012 (5) (4) 562-573; DOI: 10.1158/1940-6207.CAPR-11-0502

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Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions
Lynn Vitale-Cross, Alfredo A. Molinolo, Daniel Martin, Rania H. Younis, Takashi Maruyama, Vyomesh Patel, Wanjun Chen, Abraham Schneider and J. Silvio Gutkind
Cancer Prev Res April 1 2012 (5) (4) 562-573; DOI: 10.1158/1940-6207.CAPR-11-0502
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