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Cancer Prevention Research
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Research Article

Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis

Samriddhi Shukla, Sajid Khan, Sudhir Kumar, Sonam Sinha, Mohd. Farhan, Himangsu K. Bora, Rakesh Maurya and Syed Musthapa Meeran
Samriddhi Shukla
1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
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Sajid Khan
1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
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Sudhir Kumar
2Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
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Sonam Sinha
1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
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Mohd. Farhan
1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
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Himangsu K. Bora
3Division of Laboratory Animals, CSIR-Central Drug Research Institute, Lucknow, India.
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Rakesh Maurya
2Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
4Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
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Syed Musthapa Meeran
1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
4Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
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  • For correspondence: s.musthapa@cdri.res.in
DOI: 10.1158/1940-6207.CAPR-14-0286 Published June 2015
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Article Information

Volume 8, Issue 6, pp. 552-562

DOI 
https://doi.org/10.1158/1940-6207.CAPR-14-0286
PubMed 
25813524

Published By 
American Association for Cancer Research
Print ISSN 
1940-6207
Online ISSN 
1940-6215
History 
  • Received August 29, 2014
  • Revision received March 5, 2015
  • Accepted March 22, 2015
  • Published first March 26, 2015.

Article Versions

  • Previous version (March 26, 2015 - 12:38).
  • Previous version (May 13, 2015 - 07:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2015 American Association for Cancer Research.

Author Information

  1. Samriddhi Shukla1,
  2. Sajid Khan1,
  3. Sudhir Kumar2,
  4. Sonam Sinha1,
  5. Mohd. Farhan1,
  6. Himangsu K. Bora3,
  7. Rakesh Maurya2,4, and
  8. Syed Musthapa Meeran1,4,*
  1. 1Laboratory of Cancer Epigenetics, Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
  2. 2Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  3. 3Division of Laboratory Animals, CSIR-Central Drug Research Institute, Lucknow, India.
  4. 4Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
  1. ↵*Corresponding Author:
    Syed Musthapa Meeran, Division of Endocrinology, CSIR-Central Drug Research Institute (CSIR-CDRI), Jankipuram Extension, Sector-10, Sitapur Road, Lucknow 226 031, India. Phone: 91-5222772450, ext. 4491; Fax: 91-5222771941; E-mail: s.musthapa{at}cdri.res.in
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Cancer Prevention Research: 8 (6)
June 2015
Volume 8, Issue 6
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Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis
Samriddhi Shukla, Sajid Khan, Sudhir Kumar, Sonam Sinha, Mohd. Farhan, Himangsu K. Bora, Rakesh Maurya and Syed Musthapa Meeran
Cancer Prev Res June 1 2015 (8) (6) 552-562; DOI: 10.1158/1940-6207.CAPR-14-0286

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Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis
Samriddhi Shukla, Sajid Khan, Sudhir Kumar, Sonam Sinha, Mohd. Farhan, Himangsu K. Bora, Rakesh Maurya and Syed Musthapa Meeran
Cancer Prev Res June 1 2015 (8) (6) 552-562; DOI: 10.1158/1940-6207.CAPR-14-0286
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