Table 1.

Background characteristics of randomized subjects

Demographic variablesPlacebo (n = 68)Celecoxib (n = 69)
Age (Mean ± SD)55.8 ± 7.655.7 ± 15
Ethnicity n (%)
Asian3 (4.4%)2 (2.9%)
Black7 (10%)5 (7.2%)
Caucasian53 (78%)60 (87%)
Hispanic5 (7.3%)2 (2.9%)
Gender
Male40 (59%)38 (55%)
Female28 (41%)31 (45%)
Pack-years (Mean ± SD)44.8 ± 1542.5 ± 13.7
FMH of Lung Cancer n%14 (21%)20 (29%)
FMH of Other Cancer n%34 (50%)38 (55%)
Emphysema on CTan%*19 (28%)13 (19%)
Airflow obstructionbn%14 (21%)14 (20%)
Prior stage I NSCLC3 (4.4%)1 (1.4%)
Presence of bronchial dysplasia3 (4.4%)3 (4.3%)
Presence of squamous metaplasia15 (22%)22 (32%)

Abbreviations: FMH, family medical history; NSCLC, nonsmall cell lung cancer.

  • aPresence of emphysema on chest CT scans.

  • bFEV1/FVC <70.