Overall (n = 77) | Atorvastatin (n = 20) | Sulindac (n = 18) | ORAFTI®Synergy1 (n = 20) | Control (n = 19) | |
---|---|---|---|---|---|

Baseline | |||||

Median | 9.0 | 9.0 | 9.5 | 8.5 | 9.0 |

Range | 5–34 | 5–24 | 5–34 | 5–28 | 6–17 |

Mean | 10.3 | 10.1 | 11.1 | 10.2 | 9.7 |

SD | 5.2 | 5.0 | 6.9 | 5.5 | 3.1 |

Postintervention | |||||

Median | 8.0 | 8.0 | 7.5 | 8.5 | 8.0 |

Range | 0–41 | 3–41 | 1–27 | 1–34 | 0–20 |

Mean | 9.9 | 11.0 | 9.9 | 10.3 | 8.5 |

SD | 7.6 | 8.6 | 8.0 | 8.7 | 4.9 |

% Change^{a} | |||||

Median | −7.1 | 5.6 | −18.6 | −3.6 | −10.0 |

Range | −100 to 160 | −69 to 143 | −83 to 160 | −88 to 83 | −100 to 117 |

Mean | −5.3 | 8.4 | −13.3 | −8.8 | −8.6 |

SD | 50.3 | 49.1 | 55.4 | 49.2 | 48.8 |

P^{b} | n/a | 0.30 | 0.60 | 0.92 | n/a |

P^{c} | 0.20 | 0.59 | 0.12 | 0.54 | 0.41 |

↵

^{a}(Postintervention ACF number − baseline ACF number)/Baseline ACF number.↵

^{b}Wilcoxon rank-sum*P*value for comparison of % change in ACF between each active intervention (atorvastatin, sulindac, or ORAFTI®Synergy1) versus control.↵

^{c}Signed rank*P*value for comparison of percentage change in ACF within each randomization arm.