Table 3.

Early-stage ovarian or fallopian tube cancers identified in BRCA mutation carriers

Case no.Age at diagnosis, yBRCA1/2 mutationGradeDominant massHistologyBilateral or unilateral?Primary sizeStage
732BRCA1HighOvarySerous carcinomaBilateral12 × 6 × 6 cmIB
843BRCA1HighOvarySerous carcinomaUnknownUnknownIIA
956BRCA1HighOvarySerous carcinomaBilateral11 cmIC
1055BRCA1HighOvarySerous carcinomaUnilateral8 cmIIC
1154BRCA1HighOvaryUndifferentiated carcinomaUnilateralUnknownIA
1250BRCA1HighFallopian tubePoorly differentiated carcinomaUnilateral2 cmIA
1340BRCA1HighFallopian tubeSerous carcinomaUnilateral8 × 5 × 3 cmII
1450BRCA1HighFallopian tubeSerous carcinomaUnilateral2 × 1 × 1 cmIA
1554BRCA2HighOvaryPoorly differentiated carcinomaUnilateral7 × 7 × 5 cmIIB
1659BRCA2HighOvarySerous carcinomaBilateral7 cmIIC
1755BRCA2HighOvarySerous carcinomaBilateral14 × 7 × 6 cmIB
1850BRCA2HighOvarySerous carcinomaBilateral7 × 5 × 3 cmIIA
1961BRCA2HighOvarySerous carcinomaUnilateral15 cmIIA
2041BRCA1 and BRCA2HighOvarySerous carcinoma involving left ovary and detached fragments in RFT lumenUnilateral6 cmIIB

Abbreviation: RFT, right fallopian tube.