Table 4.

Curcumin concentrations in tissue and plasma by dose

2 g4 g
PrePostPrePost
Rectal mucosaan = 21n = 18
 Curcumin4.03 (1)8.2 ± 2.9 (5)ND3.8 ± 0.6 (3)
 ConjugatesND5.9 ± 2.6 (13)4.21 (1)4.5 ± 1.7 (12)
Plasmabn = 0n = 19
 CurcuminNANA7.3 ± 8.1 (4)3.8 ± 1.3 (2)
 ConjugatesNANA15.8 ± 14.8 (19)78.5 ± 84.3c (19)

Abbreviations: Pre, pre-intervention; Post, post-intervention; ND, not detected; NA, not assayed.

  • aMeasures are mean ± SD in μg/g protein (number of samples with detectable levels).

  • bMeasures are mean ± SD in ng/mL (number of samples with detectable levels).

  • cP = 0.009 for increased post-intervention level (versus pre-intervention level).