Table 3.

Genotype frequencies for SEP15 tag SNPs in PCa deaths and survivors and HRs and 95% confidence intervals for PCa survival analysis, adjusting for age at diagnosis

SNPGenotype frequencyHR (95% CI)
Deaths/metastases, n (%)All other cases, n (%)Codominant modelRecessive model
rs5859
    GG97 (63.8)679 (62.6)1.00 (reference)1.00 (reference)
    AG44 (29.0)359 (33.1)0.87 (0.61-1.25)1.68 (0.91-3.11)
    AA11 (7.2)47 (4.3)1.61 (0.86-3.01)
    Ptrend0.700.10
rs479341
    CC108 (62.4)698 (63.7)1.00 (reference)1.00 (reference)
    CT49 (28.3)348 (31.8)0.92 (0.65-1.28)1.94 (1.15-3.25)
    TT16 (9.3)49 (4.5)1.88 (1.11-3.19)
    Ptrend0.230.01
rs561104
    GG22 (14.1)179 (16.7)1.00 (reference)1.00 (reference)
    AG67 (43.0)545 (50.8)1.01 (0.63-1.64)1.54 (1.12-2.11)
    AA67 (43.0)348 (32.5)1.55 (0.96-2.51)
    Ptrend0.020.008
rs527281
    CC149 (85.6)971 (87.0)1.00 (reference)1.00 (reference)
    CG24 (13.8)133 (11.9)1.17 (0.76-1.80)0.65 (0.09-4.66)
    GG1 (0.6)12 (1.1)0.67 (0.09-4.76)
    Ptrend0.680.67
rs1407131
    AA121 (75.2)825 (75.1)1.00 (reference)1.00 (reference)
    AG31 (19.3)255 (23.2)0.83 (0.56-1.23)2.85 (1.45-5.59)
    GG9 (5.6)18 (1.6)2.74 (1.39-5.39)
    Ptrend0.410.002