Table 3.

Associations of three selected SNPs (rs198977, rs2735839, and rs10993994) with prostate cancer risk and plasma kallikrein values in the CAPS study

MeasureCAPS1 PCAPS2 PCombined CAPS PCAPS1 PCAPS2 PCombined CAPS PCAPS1 PCAPS2 PCombined CAPS P
rs198977 (KLK2)rs2735839 (KLK2-KLK3 intergenic region)rs10993994 (MSMB)
Cancer risk0.090.190.0290.70.20.80.30.0030.002
tPSA0.70.30.50.070.50.080.090.0550.006
fPSA0.180.30.130.20.70.50.0110.0240.0006
%fPSA0.011<0.0001<0.00010.0140.0060.00020.180.860.5
hK2<0.0001<0.0001<0.00010.80.160.30.0150.0060.0002

NOTE: Boldface indicates statistically significant results (P ≤ 0.05).