Table 4.

The association between energy balance and bladder cancer stratified by the number of unfavorable genotypes

Variables0-4 unfavorable genotypes5-6 unfavorable genotypes≥7 unfavorable genotypes
Case/controlOR (95% CI)*PCase/controlOR (95% CI)*PCase/controlOR (95% CI)*P
Energy intake
    Low82/107Reference72/85Reference60/50Reference
    Medium63/1240.75 (0.48-1.19)0.22368/801.07 (0.66-1.73)0.79061/481.19 (0.67-2.12)0.548
    High116/1261.31 (0.86-2.00)0.212135/921.66 (1.05-2.62)0.03187/382.11 (1.16-3.87)0.015
Ptrend0.1550.0260.014
Physical activity
    Intensive49/123Reference41/85Reference34/50Reference
    Medium109/1461.82 (1.17-2.84)0.008116/1132.00 (1.22-3.28)0.00695/592.01 (1.12-3.63)0.020
    Low108/952.39 (1.49-3.81)<0.001128/683.72 (2.22-6.23)<0.00182/303.45 (1.76-6.76)<0.001
Ptrend<0.001<0.001<0.001
BMI category
    Normal82/111Reference70/70Reference75/43Reference
    Overweight125/1731.02 (0.67-1.55)0.933143/1211.22 (0.77-1.92)0.39995/620.72 (0.41-1.25)0.241
    Obese59/811.00 (0.61-1.64)0.99271/750.83 (0.50-1.39)0.48243/340.54 (0.28-1.04)0.067
Ptrend0.9870.4500.065
  • *Adjusting for age, sex, tobacco smoking, energy intake, BMI, and physical activity where appropriate.