Table 1.

Characteristics of randomized patients by treatment arm

CharacteristicPCB + PCBPCB + CCXCCX + PCBCCX + CCXTotal
Total patients treated50515251204
Age (y)
    Mean ± SD53.6 ± 7.952.5 ± 9.054.3 ± 8.453.0 ± 9.553.4 ± 8.7
    Median (range)52.8 (39.6-70.4)52.4 (32.9-73.2)54.9 (39.9-73.6)52.4 (32.0-71.8)53.3 (32.0-73.6)
Gender
    Female25 (50.0%)20 (39.2%)26 (50.0%)27 (52.9%)98 (48.0%)
    Male25 (50.0%)31 (60.8%)26 (50.0%)24 (47.1%)106 (52.0%)
Race
    Black4 (8.9%)3 (5.9%)4 (7.7%)6 (11.8%)17 (8.3%)
    Hispanic1 (2.0%)3 (5.9%)05 (9.8%)9 (4.4%)
    White45 (90.0%)44 (86.3%)46 (88.5%)40 (78.4%)175 (85.8%)
    Other01 (2.0%)2 (3.8%)03 (1.5%)
Cancer history
    No46 (92.0%)45 (88.2%)43 (82.7%)48 (94.1%)182 (89.2%)
    Yes4 (8.0%)6 (11.8%)9 (17.3%)3 (5.9%)22 (10.8%)
Smoking-related cancer
    No49 (98.0%)49 (96.1%)51 (98.1%)51 (100%)200 (98.0%)
    Yes1 (2.0%)2 (3.9%)1 (1.9%)04 (2.0%)
Smoking status
    Former smokers8 (16.0%)13 (25.5%)11 (21.2%)10 (19.6%)42 (20.6%)
    Current smokers42 (84.0%)38 (74.5%)41 (78.8%)41 (80.4%)162 (79.4%)
Pack-years, mean ± SD (range)
    Former smokers46 ± 24.4 (21.3-85.2)39.8 ± 13.7 (20.6-61.5)39.8 ± 18.7 (20.4-73.9)43.6 ± 24.2 (20.0-92.6)41.9 ± 19.4 (19.9-92.6)
    Current smokers44.0 ± 14.7 (19.7-81.5)38.4 ± 18.2 (20.8-85.6)47.2 ± 17.7 (20.0-87.9)45.0 ± 22.3 (21.3-132.8)43.8 ± 18.5 (19.7-132.8)
Smoking quit-years, mean ± SD (range)9.5 ± 7.2 (1.5-18.1)7.2 ± 10.0 (1.0-33.4)9.9 ± 9.6 (1.2-35.3)9.0 ± 7.9 (1.3-23.8)8.8 ± 8.7 (1.0-35.3)
MI, mean ± SD (range)
    Former smokers6.3 ± 12.4 (0-33.3)2.6 ± 6.3 (0-16.7)4.5 ± 7.8 (0-16.7)10.0 ± 14.1 (0-33.3)5.6 ± 10.2 (0-33.3)
    Current smokers17.0 ± 24.3 (0-83.3)14.9 ± 18.9 (0-66.7)14.8 ± 19.3 (0-66.7)14.0 ± 18.5 (0-60.0)15.2 ± 20.3 (0-83.3)
Dysplasia
    No46 (92.0%)50 (98.0%)51 (98.1%)45 (88.2%)192 (94.1%)
    Yes4 (8.0%)1 (2.0%)1 (1.9%)6 (11.8%)12 (5.9%)

Abbreviations: PCB, placebo; CCX, celecoxib.