Table 3.

Celecoxib levels at 3 months by smoking status

Smoking statusCelecoxib levels
Treatmentn observedMean (μmol/L)SDMinimumMedianMaximum
CurrentCCX: 0232.113.400.001.2616.53
CCX: +1172.711.340.002.435.16
FormerCCX: 072.860.791.922.623.98
CCX: +143.233.080.642.387.50

NOTE: P = 0.78 and P = 0.004, Wilcoxon rank sum test, comparing celecoxib levels between dose levels in former (2.86 ± 0.79 versus 3.23 ± 3.08) and current (2.11 ± 3.40 versus 2.71 ± 1.34) smoker groups, respectively. P = 0.008 and P = 0.89, Wilcoxon rank sum test, comparing celecoxib levels between smoking status for dose 0 (2.11 ± 3.40 versus 2.86 ± 0.79) and +1 (2.71 ± 1.34 versus 3.23 ± 3.08) levels, respectively.

Abbreviations: CCX: 0, low-dose celecoxib; CCX: +1, high-dose celecoxib.