Table 2.

Therapeutic treatment of mouse anal cancer

CharacteristicControlRapamycin treatedP-value
Tumor incidence100%100%1.00
Cancer incidence85%100%0.16
Week of tumor onset16.7 ± 2.816.7 ± 2.60.94
Tumor size at 20th wk3.4 ± 2.12.8 ± 1.20.47
Tumor size at endpoint8.8 ± 3.55.7 ± 3.30.02
Tumor growth rate1.7 ± 1.40.5 ± 0.50.01

NOTE: Control n = 13, rapamycin treated = 12. Tumor size in mm. Growth rate in mm/wk. P-values were calculated using 2-sided chi-square test for incidence and 2-sided Wilcoxon rank sum for all other parameters.