Table 1.

Preventative treatment of mouse anal cancer

CharacteristicControlRapamycin treatedP-value
Tumor incidence100%73%0.01
Cancer incidence85%70%0.22
Week of tumor onset19.8 ± 5.120.5 ± 4.90.66
Tumor size at 20th wk3.4 ± 1.952.2 ± 1.70.06
Tumor size at endpoint7.0 ± 3.95.2 ± 3.30.13
Tumor growth rate1.5 ± 1.40.6 ± 0.60.08

NOTE: Control n = 20, rapamycin treated = 30. Tumor size in mm. Growth rate in mm/wk. P-values were calculated using 2-sided chi-square test for incidence and 2-sided Wilcoxon rank sum for all other parameters.