Table 3.

DMBA dose correlates with increase in tumor incidence and carcinogenesis in E6/E7 anal tissue

PhenotypeHistologic classification
GenotypeDose (╬╝mol)nOvert tumorAtypia (%)Cancer (%)
Nontransgenic0.12320 00 (0)0 (0)
E6/E70.1231149 (29)7 (23)
E6/E70.04300 56 (20)0 (0)
E6/E70.012310 10 (0)0 (0)
E6/E7DMSO only100 00 (0)0 (0)